Int J Nanomedicine. View abstract. Totaro, P. and Rambaldini, M. Efficacy of antimicrobial activity of slow release silver nanoparticles dressing in post-cardiac surgery mediastinitis. View abstract. Percival, S. L., Bowler, P. G., and Russell, D. Bacterial resistance to silver in wound care. J Wound Care 2007;16(3):129-132. Durucan, C. and Akkopru, B. As such, this product shouldnt be used to treat medical conditions. Induction of oxidative stress and apoptosis by silver nanoparticles in the liver of adult zebrafish. Wu, Y., Zhou, Q., Li, H., Liu, W., Wang, T., and Jiang, G. Effects of silver nanoparticles on the development and histopathology biomarkers of Japanese medaka (Oryzias latipes) using the partial-life test. In vivo wound healing and antibacterial performances of electrospun nanofibre membranes. Wadhera, A. and Fung, M. Systemic argyria associated with ingestion of colloidal silver. View abstract. View abstract. View abstract. View abstract. Braydich-Stolle, L. K., Lucas, B., Schrand, A., Murdock, R. C., Lee, T., Schlager, J. J., Hussain, S. M., and Hofmann, M. C. Silver nanoparticles disrupt GDNF/Fyn kinase signaling in spermatogonial stem cells. Chemical & Engineering News 2009;87(16):38. Yoon, K. Y., Hoon, Byeon J., Park, J. H., and Hwang, J. Susceptibility constants of Escherichia coli and Bacillus subtilis to silver and copper nanoparticles. Demonstration of the inhibition of inorganic iodine absorption by the addition of silver protein]. Int J Neurosci. View abstract. J Wound Care 2010;19(6):220-226. Eby, D. M., Luckarift, H. R., and Johnson, G. R. Hybrid antimicrobial enzyme and silver nanoparticle coatings for medical instruments. Chambers, H., Dumville, J. C., and Cullum, N. Silver treatments for leg ulcers: a systematic review. View abstract. Aquat.Toxicol. [Ophthalmia neonatorum of the newborn and its treatments in Canadian medical publications: 1872-1985]. Silver exposure in developing zebrafish produces persistent synaptic and behavioral changes. 5-15-2009;43(10):3933-3940. View abstract. This means that theyre less than 100 nanometers in size and invisible to the naked eye (6). Pal, S., Tak, Y. K., and Song, J. M. Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? View abstract. Poster presentation: Third Congress of the World Union of Wound Healing Societies, Toronto, Canada. McKenna JK, Hull CM, Zone JJ. Costa, C. S., Ronconi, J. V., Daufenbach, J. F., Goncalves, C. L., Rezin, G. T., Streck, E. L., and Paula, M. M. In vitro effects of silver nanoparticles on the mitochondrial respiratory chain. View abstract. Nanomedicine. Wiegand, C., Heinze, T., and Hipler, U. C. Comparative in vitro study on cytotoxicity, antimicrobial activity, and binding capacity for pathophysiological factors in chronic wounds of alginate and silver-containing alginate. Inhal.Toxicol. 11-12-2010; View abstract. View abstract. J Burn Care Rehabil 1995;16(3 Pt 1):241-247. 2007;8(4):1246-1254. B., Ryu, H. Y., Kim, Y. S., Song, K. S., and Yu, I. J. Histochemical study of intestinal mucins after administration of silver nanoparticles in Sprague-Dawley rats. 2010;15(4):045005. J Biol Inorg.Chem. Interact.Cardiovasc.Thorac.Surg 2009;8(1):153-154. View abstract. Environ Toxicol.Chem. View abstract. Mar.Environ Res 2010;69 Suppl:S49-S51. Anal Bioanal.Chem. Colloidal copper is a popular health supplement. J Proteome.Res 2006;5(4):916-924. Journal of Applied Sciences 2010;10(23):3132-3136. View abstract. View abstract. Toxicology 1-8-2009;255(1-2):33-37. Colloids Surf.B Biointerfaces. Controlled in-situ synthesis of silver nanoparticles in natural cellulose fibers toward highly efficient antimicrobial materials. Hinther, A., Vawda, S., Skirrow, R. C., Veldhoen, N., Collins, P., Cullen, J. T., van, Aggelen G., and Helbing, C. C. Nanometals induce stress and alter thyroid hormone action in amphibia at or below North American water quality guidelines. View abstract. Arch Toxicol. Toxicology 10-29-2009;264(3):179-184. Tura, V., Hagiu, B. (detailed description of each of the ratings). View abstract. J Burn Care Rehabil 2004;25(2):192-196. Choi, O., Clevenger, T. E., Deng, B., Surampalli, R. Y., Ross, L., Jr., and Hu, Z. 3-15-2010;44(6):2163-2168. 2009;17(4):511-521. View abstract. Li, Q., Mahendra, S., Lyon, D. Y., Brunet, L., Liga, M. V., Li, D., and Alvarez, P. J. Antimicrobial nanomaterials for water disinfection and microbial control: potential applications and implications. View abstract. Due to their ability to incite oxidation and cell damage, they may also harm healthy human cells (8, 9, 11, 12). Case report: skin discoloration following administration of colloidal silver in cystic fibrosis. Laban, G., Nies, L. F., Turco, R. F., Bickham, J. W., and Sepulveda, M. S. The effects of silver nanoparticles on fathead minnow (Pimephales promelas) embryos. Cao, X. L., Cheng, C., Ma, Y. L., and Zhao, C. S. Preparation of silver nanoparticles with antimicrobial activities and the researches of their biocompatibilities. View abstract. Deitz D and Gates J. Do not take colloidal silver if you are taking a medication that can harm the liver. Vanscheidt W, Lazareth I, and Routkovsky-Norval, C. Safety evaluation of a new ionic silver dressing in the management of chronic ulcers. View abstract. Fung MC, Weintraub M, Bowen DL. Franco-Molina, M. A., Mendoza-Gamboa, E., Sierra-Rivera, C. A., Gomez-Flores, R. A., Zapata-Benavides, P., Castillo-Tello, P., Alcocer-Gonzalez, J. M., Miranda-Hernandez, D. F., Tamez-Guerra, R. S., and Rodriguez-Padilla, C. Antitumor activity of colloidal silver on MCF-7 human breast cancer cells. View abstract. A., and Schmutzhard, E. Efficacy of silver nanoparticles-impregnated external ventricular drain catheters in patients with acute occlusive hydrocephalus. Int J Dermatol 2010;49(10):1175-1177. Rattanaruengsrikul, V., Pimpha, N., and Supaphol, P. Development of gelatin hydrogel pads as antibacterial wound dressings. Morones, J. R., Elechiguerra, J. L., Camacho, A., Holt, K., Kouri, J. Esteban-Tejeda, L., Malpartida, F., Esteban-Cubillo, A., Pecharroman, C., and Moya, J. S. The antibacterial and antifungal activity of a soda-lime glass containing silver nanoparticles. J Nanosci.Nanotechnol. View abstract. 1967;9(3):281-286. van, Hasselt P., Gashe, B. Lok, C. N., Ho, C. M., Chen, R., He, Q. Y., Yu, W. Y., Sun, H., Tam, P. K., Chiu, J. F., and Che, C. M. Proteomic analysis of the mode of antibacterial action of silver nanoparticles. At this time there is not enough scientific information to determine an appropriate range of doses for colloidal silver. Ding, T., Luo, Z. J., Zheng, Y., Hu, X. Y., and Ye, Z. X. J Am Chem.Soc 2-23-2005;127(7):2285-2291. 2009;7:8. 2010;5:753-762. Proliferation and survival of rat C6 glioma culture in the presence of implants coated with modified carbon-based films. Stepien, K. M., Morris, R., Brown, S., Taylor, A., and Morgan, L. Unintentional silver intoxication following self-medication: an unusual case of corticobasal degeneration. J Toxicol.Environ Health A 2009;72(21-22):1279-1284. Lu, L., Sun, R. W., Chen, R., Hui, C. K., Ho, C. M., Luk, J. M., Lau, G. K., and Che, C. M. Silver nanoparticles inhibit hepatitis B virus replication. Environ Sci Technol. Sigal-Grinberg, M, Senet, P, Lazareth, I., Sauvadet, A., and Bohbot, S. Evaluation of a New Contact Layer Impregnated with Silver Salts in the Management of Critically Colonized Venous Leg Ulcers. Nanotoxicology. Sudheer, Khan S., Bharath, Kumar E., Mukherjee, A., and Chandrasekaran, N. Bacterial tolerance to silver nanoparticles (SNPs): Aeromonas punctata isolated from sewage environment. Li, W. R., Xie, X. Colloidal silver might decrease how much levothyroxine the body absorbs. View abstract. Kerihuel, J. C. Effect of activated charcoal dressings on healing outcomes of chronic wounds. Chen, D., Xi, T., and Bai, J. View abstract. Toxicol.Lett 12-15-2009;191(2-3):305-313. ACS Nano. View abstract. Sheikpranbabu, S., Kalishwaralal, K., Lee, K. J., Vaidyanathan, R., Eom, S. H., and Gurunathan, S. The inhibition of advanced glycation end-products-induced retinal vascular permeability by silver nanoparticles. Galiano, K., Pleifer, C., Engelhardt, K., Brossner, G., Lackner, P., Huck, C., Lass-Florl, C., and Obwegeser, A. Kiser, M. A., Ryu, H., Jang, H., Hristovski, K., and Westerhoff, P. Biosorption of nanoparticles to heterotrophic wastewater biomass. [Effect of silver preparations on the microflora regenerated from a condensate of atmospheric water vapor in a hermetically-sealed chamber]. Gurunathan, S., Lee, K. J., Kalishwaralal, K., Sheikpranbabu, S., Vaidyanathan, R., and Eom, S. H. Antiangiogenic properties of silver nanoparticles. Sriram, M. I., Kanth, S. B., Kalishwaralal, K., and Gurunathan, S. Antitumor activity of silver nanoparticles in Dalton's lymphoma ascites tumor model. View abstract. Marinovic, Kulisic S., Lipozencic, J., Tunukovic, S., and Milavec-Puretic, V. [What should we know about venous and arterial ulcers?]. Colloidal silver proteins marketed as health supplements. Hua Xi.Kou Qiang.Yi.Xue.Za Zhi. Environ Sci Technol. Vet Hum Toxicol 2002;44:291-2.. View abstract. 1985;6 Suppl A:163-172. Cha, K., Hong, H. W., Choi, Y. G., Lee, M. J., Park, J. H., Chae, H. K., Ryu, G., and Myung, H. Comparison of acute responses of mice livers to short-term exposure to nano-sized or micro-sized silver particles. J Antimicrob.Chemother. Sheikh, F. A., Barakat, N. A., Kanjwal, M. A., Nirmala, R., Lee, J. H., Kim, H., and Kim, H. Y. Electrospun titanium dioxide nanofibers containing hydroxyapatite and silver nanoparticles as future implant materials. Although a study may suggest that colloidal silver kills certain strains of bacteria in a lab setting, this finding cant be applied to humans (8). Livingston, D. H., Cryer, H. G., Miller, F. B., Malangoni, M. A., Polk, H. C., Jr., and Weiner, L. J. Carbohydr.Res 8-16-2010;345(12):1767-1773. Issues with prostate health can negatively affect several aspects of your life. 7-22-2009;57(14):6246-6252. Chen, X. and Schluesener, H. J. Nanosilver: a nanoproduct in medical application. 1984;11(1):35-40. View abstract. J Colloid Interface Sci 4-15-2010;344(2):424-428. J Wound Care 2003;12(9):351-354. Stevens, K. N., Crespo-Biel, O., van den Bosch, E. E., Dias, A. Kim, J., Kim, S., and Lee, S. Differentiation of the toxicities of silver nanoparticles and silver ions to the Japanese medaka (Oryzias latipes) and the cladoceran Daphnia magna. Arch.Ophthalmol. Evaluation of the toxic impact of silver nanoparticles on Japanese medaka (Oryzias latipes). View abstract. 3-1-2010;76(1):50-56. View abstract. View abstract. View abstract. View abstract. [Study of digestive absorption of iodine. Journal of Clinical Rehabilitative tissue Engineering Research 2009;13(42):8373-8376. Ann Vasc.Surg 2007;21(5):598-602. View abstract. [Preparation and antibacterial capacity of artificial skin loaded with nanoparticles silver using bacterial cellulose]. View abstract. Development of silver-zein composites as a promising antimicrobial agent. View abstract. View abstract. View abstract. Silver is also thought to interfere with proteins found within viruses, which may prevent the viruss replication (8, 9, 10). Gogoi, S. K., Gopinath, P., Paul, A., Ramesh, A., Ghosh, S. S., and Chattopadhyay, A. Its unknown exactly how colloidal silver works. A liposome hydrogel with polyvinyl-pyrrolidone iodine in the local treatment of partial-thickness burn wounds. View abstract. Kim, K. J., Sung, W. S., Moon, S. K., Choi, J. S., Kim, J. G., and Lee, D. G. Antifungal effect of silver nanoparticles on dermatophytes. View abstract. J Phys Chem.B 8-24-2006;110(33):16248-16253. However, no scientific research supports this. Kemp, M. M., Kumar, A., Mousa, S., Dyskin, E., Yalcin, M., Ajayan, P., Linhardt, R. J., and Mousa, S. A. Gulbranson SH, Hud JA, Hansen RC. Here is a list of 4 natural supplements that are just as effective as pharmaceutical drugs. View abstract. View abstract. Colloidal silver is a suspension of silver particles in a liquid. 2010;32(3):391-397. Proceedings of the 17th Conference of the European Wound Management Association. J Nanobiotechnology. Mol.Pharm 2009;6(5):1388-1401. Powers, C. M., Badireddy, A. R., Ryde, I. T., Seidler, F. J., and Slotkin, T. A. A prospective clinical trial of wound dressings to investigate the rate of infection under occlusion. Tang, J., Xiong, L., Wang, S., Wang, J., Liu, L., Li, J., Yuan, F., and Xi, T. Distribution, translocation and accumulation of silver nanoparticles in rats. A. and Caldwell, D. R. Corneal argyrosis: histologic, ultrastructural and microanalytic study. Environ Sci Technol. J Clin Nurs. J Wound Care 2004;13(4):154-155. Z.Krebsforsch. Chae, Y. J., Pham, C. H., Lee, J., Bae, E., Yi, J., and Gu, M. B. Next to red peppers, you can get the most vitamin C from ________________. Zhongguo Yi.Liao.Qi Xie.Za Zhi. You are encouraged to report negative side effects of prescription drugs to the FDA. 2-24-2009;3(2):279-290. View abstract. View abstract. However, the environmental and health risks of silver nanoparticles arent well understood, and ingesting colloidal silver is considered unsafe. 2010;5:505-515. View abstract. J Microbiol.Biotechnol. View abstract. Tian, J., Wong, K. K., Ho, C. M., Lok, C. N., Yu, W. Y., Che, C. M., Chiu, J. F., and Tam, P. K. Topical delivery of silver nanoparticles promotes wound healing. 1-17-2011;101(1):117-125. Gou, N., Onnis-Hayden, A., and Gu, A. Tredget, E. E., Shankowsky, H. A., Groeneveld, A., and Burrell, R. A matched-pair, randomized study evaluating the efficacy and safety of Acticoat silver-coated dressing for the treatment of burn wounds. The synthesis of chitosan-based silver nanoparticles and their antibacterial activity. View abstract. Environ Health Perspect. Colloids Surf.B Biointerfaces. Toxicol.Sci 2009;108(2):223-224. J Colloid Interface Sci 11-1-2007;315(1):389-395. Aquat.Toxicol. Acta Clin Belg. View abstract. B. What is colloidal silver, and why is it used? View abstract. View abstract. 2010;5:261-267. Toxicol.Sci 2010;115(2):521-534. 2010;8:15. However, the exact amounts and timeframe arent known (14). Acta Biomater. Gopinath, P., Gogoi, S. K., Sanpui, P., Paul, A., Chattopadhyay, A., and Ghosh, S. S. Signaling gene cascade in silver nanoparticle induced apoptosis. G.Ital.Med Lav.Ergon. 2007;2(1):129-136. To date, no research supports the use of oral colloidal silver in the prevention, treatment, or cure of any health condition or disease. Balantrapu, K. and Goja, D. V. Silver nanoparticles for printable electronics and biological applications. A silver-based antimicrobial. Valodkar, M., Bhadoria, A., Pohnerkar, J., Mohan, M., and Thakore, S. Morphology and antibacterial activity of carbohydrate-stabilized silver nanoparticles. Last medically reviewed on January 19, 2022. Lamb, J. G., Hathaway, L. B., Munger, M. A., Raucy, J. L., and Franklin, M. R. Nanosilver particle effects on drug metabolism in vitro. Sur, I., Cam, D., Kahraman, M., Baysal, A., and Culha, M. Interaction of multi-functional silver nanoparticles with living cells. Iran Biomed.J 2010;14(1-2):23-32. 10-15-2010;100(2):151-159. University of Washington. Karcioglu, Z. 2010;118(1):73-79. View abstract. Here are the 7 best prostate health supplements. View abstract. Ostomy.Wound Manage. What Is Japanese Knotweed, and Should You Try It. 6-9-2010;2(6):942-952. Investigation of the interactions between silver nanoparticles and Hela cells by scanning electrochemical microscopy. Honey compared with 1% silver sulfadiazine cream in the treatment of superficial and partial thickness burns. Sadhasivam, S., Shanmugam, P., and Yun, K. Biosynthesis of silver nanoparticles by Streptomyces hygroscopicus and antimicrobial activity against medically important pathogenic microorganisms. Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings). Hsin, Y. H., Chen, C. F., Huang, S., Shih, T. S., Lai, P. S., and Chueh, P. J. View abstract. View abstract. 11-23-2010;4(11):6903-6913. 6-15-2008;42(12):4583-4588. 11-1-2010; View abstract. A case of argyria after colloidal silver ingestion. View abstract. B.H. Try this today: Not all alternative medicine therapies are unsafe, though the best course of action if you have a serious health condition is to consult your doctor for a treatment regimen. J Nanobiotechnology. View abstract. Taking colloidal silver along with medications that might also harm the liver can increase the risk of liver damage. 4-28-2009;3(4):984-994. View abstract. Navarro, E., Piccapietra, F., Wagner, B., Marconi, F., Kaegi, R., Odzak, N., Sigg, L., and Behra, R. Toxicity of silver nanoparticles to Chlamydomonas reinhardtii. View abstract. View abstract. J Trauma 1990;30(7):857-865. View abstract. Colloidal silver might decrease how much penicillamine your body absorbs. Further, no human data supports consuming colloidal silver to treat or prevent medical conditions like diabetes, cancer, HIV, digestive issues, and other illnesses (8). Alt, V., Bechert, T., Steinrucke, P., Wagener, M., Seidel, P., Dingeldein, E., Domann, E., and Schnettler, R. An in vitro assessment of the antibacterial properties and cytotoxicity of nanoparticulate silver bone cement. Vasilev, K., Sah, V. R., Goreham, R. V., Ndi, C., Short, R. D., and Griesser, H. J. Antibacterial surfaces by adsorptive binding of polyvinyl-sulphonate-stabilized silver nanoparticles. B. Storm-Versloot, M. N., Vos, C. G., Ubbink, D. T., and Vermeulen, H. Topical silver for preventing wound infection. Saxena, S., Ray, A. R., Kapil, A., Pavon-Djavid, G., Letourneur, D., Gupta, B., and Meddahi-Pelle, A. A nose-to-nose comparison of the physiological effects of exposure to ionic silver versus silver chloride in the European eel (Anguilla anguilla) and the rainbow trout (Oncorhynchus mykiss). Int Wound J 2009;6(4):275-284. Juan, L., Zhimin, Z., Anchun, M., Lei, L., and Jingchao, Z. Deposition of silver nanoparticles on titanium surface for antibacterial effect. Sawosz, E., Binek, M., Grodzik, M., Zielinska, M., Sysa, P., Szmidt, M., Niemiec, T., and Chwalibog, A. View abstract. Hybrid nanofibrous yarns based on N-carboxyethylchitosan and silver nanoparticles with antibacterial activity prepared by self-bundling electrospinning. View abstract. Ji, J. H., Jung, J. H., Kim, S. S., Yoon, J. U., Park, J. D., Choi, B. S., Chung, Y. H., Kwon, I. H., Jeong, J., Han, B. S., Shin, J. H., Sung, J. H., Song, K. S., and Yu, I. J. Twenty-eight-day inhalation toxicity study of silver nanoparticles in Sprague-Dawley rats. Shrivastava, S., Bera, T., Singh, S. K., Singh, G., Ramachandrarao, P., and Dash, D. Characterization of antiplatelet properties of silver nanoparticles. Proponents of colloidal silver claim that it can prevent, cure, and treat many diseases and ailments. DVORAK, V. [Is Crede's method still necessary?]. View abstract. Ward, T. J., Kramer, J. R., Boeri, R. L., and Gorsuch, J. W. Chronic toxicity of silver to the sea urchin (Arbacia punctulata). Biotechnol.Lett 2008;30(11):1893-1899. View abstract. Construction of antibacterial multilayer films containing nanosilver via layer-by-layer assembly of heparin and chitosan-silver ions complex. Sheng Wu Yi.Xue.Gong.Cheng Xue.Za Zhi. View abstract. Aquat.Toxicol. Keep in mind that natural products are not always necessarily safe and dosages can be important. 10-15-2009;55(10):24-26. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. Jain, P. and Pradeep, T. Potential of silver nanoparticle-coated polyurethane foam as an antibacterial water filter. J Burn Care Rehabil 1990;11(1):35-41. 2008; Ph.D: pages unknown. Biomaterials 2010;31(26):6796-6808. Mirsattari, S. M., Hammond, R. R., Sharpe, M. D., Leung, F. Y., and Young, G. B. Myoclonic status epilepticus following repeated oral ingestion of colloidal silver. Gerding, R. L., Emerman, C. L., Effron, D., Lukens, T., Imbembo, A. L., and Fratianne, R. B. Outpatient management of partial-thickness burns: Biobrane versus 1% silver sulfadiazine. View abstract. Reducing the Toxicity of Antimicrobial Silver. View abstract. Martin, W. J. Etheric biology. EWMA Journal 2008;244. A study of the Gram-negative bacterium Escherichia coli. Injury 2010;41(5):522-527. Am J Ind.Med 2009;52(3):246-250. Rai, M., Yadav, A., and Gade, A. 4-29-2010; View abstract. View abstract. Wang JW and Teng YJ. View abstract. View abstract. View abstract. The size of the silver particles in colloidal silver varies, but some are so tiny that theyre referred to as nanoparticles. 2010;4(3):319-330. View abstract. Kwon, H. B., Lee, J. H., Lee, S. H., Lee, A. Y., Choi, J. S., and Ahn, Y. S. A case of argyria following colloidal silver ingestion. View abstract. Nanotoxicology. Baker, C. D., Federico, M. J., and Accurso, F. J. Colloids Surf.B Biointerfaces. (Lond) 2008;3(5):627-635. A Comparison of Three Silver-containing Dressings in the Treatment of Infected, Chronic Wounds. View abstract. Apt, L. and Isenberg, S. Chemical preparation of skin and eye in ophthalmic surgery: an international survey. 2009;25(2):206-213. 8-12-2010;19(15):S32-S36. View abstract. New in-vitro study data show importance of dressing conformability to action of silver-containing wound dressing. 12-18-2009;390(3):733-737. Panacek, A., Kvitek, L., Prucek, R., Kolar, M., Vecerova, R., Pizurova, N., Sharma, V. K., Nevecna, T., and Zboril, R. Silver colloid nanoparticles: synthesis, characterization, and their antibacterial activity. Federal Practitioner 2004;April:9-17. 11-1-2010; View abstract. View abstract. Environ Sci Technol. Barnea, Y., Weiss, J., and Gur, E. A review of the applications of the hydrofiber dressing with silver (Aquacel Ag) in wound care. Ahamed, M., Posgai, R., Gorey, T. J., Nielsen, M., Hussain, S. M., and Rowe, J. J. 11-1-2010;44(21):8337-8342. Samberg, M. E., Orndorff, P. E., and Monteiro-Riviere, N. A. Antibacterial efficacy of silver nanoparticles of different sizes, surface conditions and synthesis methods. Gold and silver nanoparticles conjugated with heparin derivative possess anti-angiogenesis properties. Appl Environ Microbiol. View abstract. J Wound Care 2010;19(1):20-26. Suresh, A. K., Pelletier, D. A., Wang, W., Moon, J. W., Gu, B., Mortensen, N. P., Allison, D. P., Joy, D. C., Phelps, T. J., and Doktycz, M. J. Biomacromolecules. J Burn Care Res 2006;27(3):298-309. View abstract. Gangadharan, D., Harshvardan, K., Gnanasekar, G., Dixit, D., Popat, K. M., and Anand, P. S. Polymeric microspheres containing silver nanoparticles as a bactericidal agent for water disinfection. J Nanosci.Nanotechnol. Environmental Toxicology & Pharmacology 2010;30(2):162-168. Foldbjerg, R., Olesen, P., Hougaard, M., Dang, D. A., Hoffmann, H. J., and Autrup, H. PVP-coated silver nanoparticles and silver ions induce reactive oxygen species, apoptosis and necrosis in THP-1 monocytes. Sotiriou, G. A. and Pratsinis, S. E. Antibacterial activity of nanosilver ions and particles. Bezemer, G. F., Bauer, S. M., Oberdorster, G., Breysse, P. N., Pieters, R. H., Georas, S. N., and Williams, M. A. Activation of Pulmonary Dendritic Cells and Th2-Type Inflammatory Responses on Instillation of Engineered, Environmental Diesel Emission Source or Ambient Air Pollutant Particles in vivo. A., Rajakumar, G., Marimuthu, S., Bagavan, A., Jayaseelan, C., Zahir, A. Woods, E. J., Cochrane, C. A., and Percival, S. L. Prevalence of silver resistance genes in bacteria isolated from human and horse wounds. Elliott, C. The effects of silver dressings on chronic and burns wound healing. View abstract. View abstract. View abstract. 6-23-2009;3(6):1357-1364. Ivins, N., Jorgensen, B., Lohmann, M., Harding, K. G., Price, P., Gottrup, F., Andersen, K. E., Bech-Thomsen, N., Scanlon, E., Roed-Petersen, J., Kirsner, R., Charles, C., Romanelli, M., Mastronicola, D., Rheinen, H., Leaper, D., Neumann, H. A. M., Munte, K., Veraart, J., Ceulen, R., Coerper, S., and Sibbald, G. Safety and efficacy in long term use of a sustained silver-releasing foam dressing: a randomised, controlled trial on venous leg ulcers. A. Fractionating nanosilver: importance for determining toxicity to aquatic test organisms. View abstract. Melaiye, A., Sun, Z., Hindi, K., Milsted, A., Ely, D., Reneker, D. H., Tessier, C. A., and Youngs, W. J. 2010;398(2):867-876. Santoro, C. M., Duchsherer, N. L., and Grainger, D. W. Antimicrobial efficacy and ocular cell toxicity from silver nanoparticles. Tidsskr.Nor Laegeforen. Arch Anim Nutr 2007;61(6):444-451. Comparison of the ionic silver-containing hydrofiber and paraffin gauze dressing on split-thickness skin graft donor sites. In fact, the FDA deemed that all over-the-counter products that contain colloidal silver ingredients or silver salts are not generally recognized as safe or effective (1, 2). Appl Microbiol.Biotechnol. View abstract. Argyria following the use of dietary supplements containing colloidal silver protein. While argyria isnt inherently harmful, its irreversible and likely permanent. If you use silver frequently on an open wound, you may experience localized argyria due to a buildup of silver in the surrounding tissue though this condition is rare (18). Colloids Surf.B Biointerfaces. View abstract. 3-1-2000;48(2-3):327-342. B., van der Veen, F. H., Maessen, J. G., Stobberingh, E. E., and Koole, L. H. The relationship between the antimicrobial effect of catheter coatings containing silver nanoparticles and the coagulation of contacting blood. Colloidal silver is the term used to describe tiny particles of silver suspended in a liquid (1). View abstract. View abstract. 11-1-2010;44(21):8314-8321. 7-1-2010;44(13):5210-5215. View abstract. Colloidal silver is a popular remedy in alternative medicine. 11-1-2010;81(1):358-362. Shavandi, Z., Ghazanfari, T., and Moghaddam, K. N. In vitro toxicity of silver nanoparticles on murine peritoneal macrophages. View abstract. View abstract. Sci Total Environ 11-1-2010;408(23):5817-5823. Coutts, P. and Sibbald, R. G. The effect of a silver-containing Hydrofiber dressing on superficial wound bed and bacterial balance of chronic wounds. Jude, E. B., Apelqvist, J., Spraul, M., and Martini, J. Influence of hydrocolloidal silver nanoparticles on gastrointestinal microflora and morphology of enterocytes of quails. Diabet.Med 2007;24(3):280-288. Thomas, V., Yallapu, M. M., Sreedhar, B., and Bajpai, S. K. A versatile strategy to fabricate hydrogel-silver nanocomposites and investigation of their antimicrobial activity. View abstract. View abstract. Colloids Surf.B Biointerfaces. Caruso, D. M., Foster, K. 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